How much water should I take Transfer Factor Max with?

8 oz (240 ml), which is what the label specifies. That is not an arbitrary number: a full glass helps four capsules clear the esophagus rather than lodging, and it aids capsule dissolution. Taking capsules with a sip of water or dry, especially lying down, is a common cause of pill-induced irritation. Stay upright for a few minutes after taking them.*

What if I miss a dose of Transfer Factor Max — should I double up?

No. Skip the missed serving and resume the normal four capsules the next day. There is no evidence that doubling recovers anything, and it doubles the zinc in a single sitting, which is the ingredient most likely to cause nausea at higher single doses. Nothing about the product's proposed mechanism suggests a missed day needs compensating for.*

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Routine, Explained

When to Take Transfer Factor Max: Timing, Food, Water and Dosing

Q: When should I take Transfer Factor Max?

4Life's official directions are to take four vegetable capsules with 8 oz (240 ml) of water daily, and for best results to take them with food. The label does not specify a time of day, and no study has compared morning dosing against evening dosing for this product. If you want a defensible default, mornings with breakfast is the reasonable choice: it matches the conditions of the one peer-reviewed human trial behind the two-hour activation claim, which ran clinic visits between 7:00 and 11:00 a.m. with participants who had eaten a light breakfast and who took the encapsulated product with water. That is a match of conditions, not proof that morning works better. The single most important factor is taking it consistently every day.*

Q: Should I take Transfer Factor Max with food or on an empty stomach?

With food. That is 4Life's own recommendation, and each of the formula's non-peptide ingredients points the same direction. Vitamin D3 is fat-soluble and absorbs better from a meal containing fat than from a fat-free one. Zinc is technically absorbed better on an empty stomach, but zinc on an empty stomach is a well-known cause of nausea, and a dose you cannot tolerate is worth nothing. Food also buffers stomach acid, which is at least theoretically relevant for colostrum- and egg-derived peptides. The one ingredient with direct human timing data, IP-6, showed no meaningful absorption difference between an empty and a full stomach in a small six-person study.*

Q: Can I take Transfer Factor Max at night?

Yes. Nothing on the label prohibits evening dosing, and no study of this product has compared evening to morning. Immune-cell counts do follow a daily rhythm — the peer-reviewed 2024 trial deliberately scheduled every blood draw at matched morning times precisely to keep circadian variation from confounding its results — but that is a reason researchers control for time of day, not evidence that a particular time makes a supplement work better. If evening is when you will actually remember to take it, take it in the evening with dinner. Consistency beats optimization here. One practical caution: if you take it late on an empty stomach and find the zinc unsettles your stomach, move it to a meal.*

Q: Can I split the four capsules into two doses?

There is no evidence either way, and no study has tested a split serving of this product. The label defines a serving as four capsules taken daily. Two things are worth knowing. First, the peer-reviewed trial that produced the widely repeated two-hour finding gave participants a single encapsulated serving at one sitting, so a single daily serving is the only pattern with any human data behind it. Second, splitting doses is genuinely useful for nutrients with saturable absorption at high intakes — vitamin C is the classic example — but the vitamin C dose in this formula is a supporting amount, not a gram-level one, so the argument does not really apply. If splitting the serving between breakfast and dinner is what makes you take it every day, the practical cost is likely nil. If you want to follow the label exactly, take all four together.*

Q: Can I take Transfer Factor Max with my other supplements?

In most cases yes, with one practical note. Transfer Factor Max contains zinc at 90% of the Daily Value plus IP-6, which is chemically the same compound as phytic acid and binds minerals. If you also take a separate zinc, iron, calcium or magnesium supplement, spacing those a few hours apart from Max is a low-cost precaution. There is no human study testing that combination in either direction, so this is a sensible-caution recommendation rather than a proven interaction. Anyone taking prescription medication, particularly immunosuppressants, should talk to a healthcare provider before adding an immune-active supplement.*

Q: Does it matter what kind of food I take it with?

Slightly, and mostly for the vitamin D3. Vitamin D is fat-soluble, and research from Dawson-Hughes and colleagues found peak absorption of supplemental vitamin D3 averaged about 32% higher when taken with a meal containing a typical amount of fat than with a fat-free meal. So a breakfast with some fat — eggs, yogurt, nuts, avocado — is a marginally better vehicle than dry toast or black coffee. Keep the size of that effect in perspective: a separate study found meal conditions changed measured absorption of vitamin D3 without changing the plasma 25-hydroxyvitamin D response, which is the number that reflects your actual vitamin D status. Any real meal is fine.*

Q: How long does Transfer Factor Max take to work?

This question needs an honest split answer. In the laboratory sense, the peer-reviewed 2024 trial measured changes in immune-surveillance biomarkers within one to two hours of a single serving. But a biomarker moving in a blood sample is not the same thing as a person feeling different, and no trial has measured how anyone felt at any time point. There is no established timeline for subjective effects because subjective effects have not been studied. Practically: one bottle is 120 capsules, or a 30-day supply at four per day, and 4Life offers a 30-day money-back guarantee — so a bottle is roughly the natural evaluation window.*

TransferFactorMax.com Editorial Updated August 14, 2026 9-min read

TL;DR

The label: four vegetable capsules with 8 oz (240 ml) of water, daily — "for best results, take with food." No time of day is specified.
Morning is the defensible default — not because morning is proven better, but because it matches the conditions of the one peer-reviewed human trial: 7–11 a.m. clinic visits, a light breakfast, capsules taken with water.
Take it with food. Every non-peptide ingredient in the formula points the same way, and the vitamin D3 genuinely absorbs better with some fat.*
Don't double up after a missed day, don't exceed four capsules, and space separate mineral supplements a few hours out.
Consistency beats optimization. No study has compared morning to night, split to single, or coffee to water for this product.

4Life Transfer Factor® Max is a daily immune-support supplement taken as four vegetable capsules with 8 oz of water, ideally with food, according to the manufacturer's directions for use.¹ One bottle contains 120 capsules — thirty four-capsule servings, or a 30-day supply. Beyond that, 4Life's label is silent on the questions customers actually ask: morning or night, with what kind of meal, all four at once or split, and what to do about a missed day.

This piece answers those questions the way we've answered every other one on this site — by saying what the evidence supports, what it doesn't, and where the record simply runs out. Some of the honest answers here are "nobody knows." Those are the useful ones, because the pages telling you a precise optimal hour are inventing it.

Transfer Factor Max — dosing at a glance

Serving size: Four (4) vegetable capsules
Frequency: Once daily
Water: 8 oz / 240 ml, per label
With food?: Yes — "for best results, take with food"
Time of day: Not specified by the manufacturer
Bottle size: 120 capsules · 30 servings · 30-day supply
Guarantee: 30-day money-back guarantee

What the label says — and what it leaves out

4Life's Directions for Use are one sentence: "Take four (4) capsules with 240 ml (8 oz) water daily. For best results, take with food."¹ That is the entire official protocol.

It is a good instruction as far as it goes. It fixes the amount, the vehicle, and the meal context. What it doesn't do is address timing, splitting, missed doses, or interactions with the rest of your routine — which is exactly where affiliate pages tend to fill the vacuum with confident-sounding advice that has no source. So let's start with the one piece of real evidence that touches timing at all.

The study that gives you a genuine timing clue Peer-reviewed

The most-cited claim about this product family — that 4Life Transfer Factor is "clinically proven to activate the immune system within two hours" — traces to a single peer-reviewed paper: Yu, Iloba, Cruickshank and Jensen, published in Current Issues in Molecular Biology in 2024.² We walk through what that study did and didn't show in our breakdown of the clinical studies behind Max.

What almost nobody mentions is the trial's protocol, and it happens to be the closest thing to timing guidance that exists for this ingredient. Reading the methods section:

Morning. Every clinic visit was scheduled between 7:00 and 11:00 a.m., with participants arriving in staggered 15-minute slots and blood drawn on a strict schedule. The researchers state plainly why: to minimize the effect of circadian fluctuations on immune measurements.
After a light breakfast. Enrollment required a "consistent habit of bland breakfasts on days of clinic visits" — so participants had eaten, and eaten something unremarkable.
With water, as capsules. "An encapsulated test product was provided with water and consumed in the presence of clinic staff." Participants were told to drink water only during the visit.
At rest. No exercise and no other supplements on the morning of a visit; participants sat calmly for three hours, because exercise and stress are known to move lymphocytes around independently of anything you swallow.

So the two-hour finding was produced in the morning, on a light breakfast, with a glass of water, in a person sitting still. If you want your own routine to resemble the conditions under which the effect was actually measured, that's the recipe — and, conveniently, it costs nothing to follow.

Matching the study conditions is not the same as proving those conditions are optimal. No trial has ever compared morning dosing to evening dosing for this product.

Say that clearly, because the distinction matters: the researchers controlled for time of day to keep circadian noise out of their results, not to demonstrate that morning is better. Immune-cell counts genuinely do vary across the day, which is why serious immunology studies fix the hour. Whether that translates into a better or worse outcome from a supplement taken at a particular hour is an open research question, and anyone who tells you otherwise about this product is going beyond the record.

Why "with food" is the right default

4Life recommends food, and unusually, you can check that recommendation ingredient by ingredient. Max isn't only transfer factor peptides — it also carries zinc at 90% of the Daily Value, vitamin C, high-potency vitamin D3, IP-6 and a super-mushroom blend.¹ Four of those have relevant absorption literature, and they don't all point the same direction.

Vitamin D3 — the clearest case for food

Vitamin D is fat-soluble, and it behaves like it. Dawson-Hughes and colleagues reported that peak (12-hour) absorption of supplemental vitamin D3 was on average about 32% higher when taken with a meal containing a commonly consumed amount of fat than with a fat-free meal.³ That's a real, replicated-in-principle effect, and it's the single best reason to swallow these capsules alongside actual breakfast rather than black coffee.

The honest counterweight: a separate study found that meal conditions changed the measured absorption of supplemental vitamin D3 without changing the plasma 25-hydroxyvitamin D response — the number that reflects your actual vitamin D status.⁴ So take the food advice, but don't agonize over the menu.

Zinc — the tolerability trade

Zinc is the ingredient that cuts the other way. Mineral absorption is generally better on an empty stomach, with less competition from other dietary components — but zinc on an empty stomach is a well-documented cause of nausea and stomach upset, because zinc salts can irritate the gastric lining directly. A slightly lower absorption you can actually tolerate every day beats a theoretically better one that makes you skip doses.

There's a second wrinkle specific to this formula, and it's the one nobody else on this keyword mentions. IP-6 is chemically identical to phytic acid — the compound nutrition science calls an antinutrient precisely because it binds minerals like zinc.⁵ In Max, IP-6 and zinc are in the same capsule. We covered this at length in our IP-6 deep dive, and the conclusion there holds here: the interaction is chemically real, its clinical significance is unsettled, and no human study has tested this combination in either direction. The practical takeaway is unchanged — the phytate already inside the capsule matters more than the phytate in your oatmeal, so choose your meal for tolerance, and space any separate mineral supplements a few hours away.

Vitamin C — saturable, but not at this dose

Vitamin C absorption is saturable, which is the real pharmacological basis for splitting doses. Levine and colleagues established that oral doses up to roughly 200 mg are essentially completely absorbed, while bioavailability falls away at higher intakes — down to about a third at a single 1,250 mg dose.⁶ That's a genuine argument for dividing gram-level vitamin C. It is not an argument for dividing this product: 4Life describes the vitamin C in Max as a supporting antioxidant ingredient, not a mega-dose, and does not publish the milligram amount.

IP-6 — the one ingredient with direct timing data

Grases and colleagues gave six healthy volunteers a 400 mg dose of IP-6 on an empty stomach, on an empty stomach with an alkalinising agent, and on a full stomach — and found no meaningful difference in absorption between conditions.⁷ Six people is a small study and it measured absorption of IP-6 itself rather than the mineral consequences, but as far as it goes, it says food neither helps nor hurts this ingredient.

The peptides themselves — the acid question

The 900 mg of transfer factor peptides is what you're actually buying, so it's fair to ask whether food protects them. Here the honest answer is that the directly relevant research doesn't exist. What exists is adjacent: a review of orally administered immunoglobulin preparations found that bovine IgG survives gastric exposure and resists proteolytic digestion well enough that anywhere from trace amounts up to about 25% is recovered intact in stool.⁸ Food buffers stomach acid, which plausibly helps anything acid-sensitive.

Two caveats keep this from being a claim. First, 4Life's transfer factors are described as low-molecular-weight peptides, not intact immunoglobulins, so the IgG survival literature is a neighbor, not a proxy. Second, nobody has published a study of transfer factor peptide survival with versus without a meal. "Food probably doesn't hurt and may buffer acid" is as far as the evidence carries.

What no one can honestly tell you

There is no published study comparing morning versus evening dosing of Transfer Factor Max, no study of a split serving, no study of taking it with coffee, and no study measuring how people feel at any time point. Everything in this article is either the manufacturer's own instruction, the documented conditions of a published trial, or general absorption science applied to a named ingredient — labelled as such. If a page gives you a precise optimal hour for this product, ask which study it came from.*

The questions the label doesn't answer

Timing and dosing — evidence vs. practical answer

Question	What the evidence says	Practical answer
Morning or night?	No head-to-head study. The peer-reviewed trial ran mornings, 7–11 a.m., and controlled for circadian variation.	Morning with breakfast — matches the studied conditions. Evening is fine if that's when you'll remember.
With food or fasted?	Vitamin D3 absorbs ~32% better with fat;³ zinc absorbs better fasted but commonly causes nausea; IP-6 unaffected.⁷	With food — 4Life's own recommendation, and the balance of the ingredient evidence.
Split the four capsules?	Untested. The trial gave one encapsulated serving at a sitting. Splitting helps saturable nutrients at gram doses; not applicable here.	All four together per the label. Split only if it's the difference between taking it and not.
How much water?	Label specifies 8 oz / 240 ml. Swallowing capsules dry or with a sip is a known cause of pill-induced irritation.	A full glass, sitting or standing upright. Easy and non-negotiable.
Missed a day?	No evidence that doubling recovers anything; a double serving doubles the zinc in one sitting.	Skip it. Resume four capsules the next day.
Take with coffee?	Untested for this product. Coffee and tea polyphenols can modestly reduce absorption of some minerals.	Use water, as the label says. Have the coffee alongside.
With other supplements?	No human study of Max with separate mineral supplements. IP-6 binds minerals; Max already contains 90% DV zinc.	Space separate zinc, iron, calcium or magnesium a few hours out. Sensible caution, not a proven interaction.
More than four capsules?	No study of any higher serving. Dose-ranging work on immune-active mushroom extracts has reported effects in both directions depending on dose.	Stay at four unless a healthcare provider says otherwise.

"Practical answer" is our editorial team's reading, and where a cell is highlighted it means the recommendation rests on either the manufacturer's own directions or published absorption research — not on a study of this product at that timing. Where nothing is highlighted, we're telling you the honest answer is unstudied.

A routine that actually survives contact with a weekday

Strip the science back and there are only three decisions worth making, in this order.

Pick the meal you never skip. For most people that's breakfast or dinner. Attach the four capsules to it permanently. The adherence research on daily supplements is consistent and unglamorous: the meal you already eat is a far better cue than an alarm.
Put the bottle where that meal happens. Kitchen counter, not bathroom cabinet — and check the storage guidance on your bottle rather than parking it above the stove.
Use a real glass of water. 8 oz, upright, and give it a minute before lying down.

If you want the version that mirrors the published trial as closely as a normal life allows: four capsules with a breakfast that contains some fat, a full glass of water, before the day gets going. If mornings are chaos, dinner is the better plan — because the routine you keep is worth more than the routine you optimize and abandon.

Mistakes worth avoiding

Doubling after a missed day. No upside, and it stacks zinc.
Taking it dry or lying down. Four capsules and a sip of water is how people end up with an irritated esophagus.
Stacking it with a separate zinc supplement at the same moment. Max already provides 90% of the Daily Value; adding more in the same sitting isn't obviously useful and may be counterproductive.
Expecting to feel the two-hour effect. That finding is a biomarker measured in a blood sample, not a sensation. No study has measured how anyone felt, at two hours or at any other point.*
Restarting the clock every time you switch routines. A bottle is 30 days. Give a consistent routine that long before judging it — which happens to line up with the 30-day money-back guarantee.

For the full formula breakdown, see what's inside Transfer Factor Max. For the proposed mechanism behind the peptides themselves — Recognize, Respond, Remember, Renew — see the science page, and for quick answers on ordering, shipping and the guarantee, see the FAQ.

Frequently asked questions

When should I take Transfer Factor Max?

4Life's directions are four vegetable capsules with 8 oz (240 ml) of water daily, and "for best results, take with food." No time of day is specified, and no study has compared morning to evening for this product. If you want a defensible default, mornings with breakfast matches the conditions of the one peer-reviewed human trial behind the two-hour claim — clinic visits between 7:00 and 11:00 a.m., participants who'd eaten a light breakfast, capsules taken with water. That's a match of conditions, not proof morning is better. Consistency matters far more.*

Should I take Transfer Factor Max with food or on an empty stomach?

With food — 4Life's own recommendation, and the ingredients back it. Vitamin D3 is fat-soluble and absorbs better from a meal containing fat. Zinc technically absorbs better fasted, but zinc on an empty stomach is a well-known cause of nausea, and a dose you can't tolerate is worth nothing. Food also buffers stomach acid, which is at least theoretically relevant for colostrum- and egg-derived peptides. IP-6, the one ingredient with direct human timing data, showed no meaningful absorption difference between an empty and a full stomach.*

Can I take Transfer Factor Max at night?

Yes. Nothing on the label prohibits it, and no study of this product has compared evening to morning. Immune-cell counts do follow a daily rhythm — the 2024 trial scheduled every blood draw at matched morning times precisely to keep circadian variation out of its results — but that's a reason researchers control for time of day, not evidence that a particular hour makes a supplement work better. If evening is when you'll actually remember, take it with dinner. One caution: if late-night dosing on an empty stomach unsettles you, that's the zinc — move it to a meal.*

Can I split the four capsules into two doses?

There's no evidence either way; no study has tested a split serving. The label defines a serving as four capsules daily, and the peer-reviewed trial gave a single encapsulated serving at one sitting — so a single daily serving is the only pattern with human data behind it. Splitting is genuinely useful for nutrients with saturable absorption at high intakes (vitamin C is the classic case), but the vitamin C here is a supporting amount, not a gram-level one, so the argument doesn't really apply. If splitting between breakfast and dinner is what makes you take it every day, the practical cost is likely nil.*

How much water should I take it with?

8 oz (240 ml) — what the label specifies, and not an arbitrary number. A full glass helps four capsules clear the esophagus rather than lodging, and aids dissolution. Taking capsules dry or with a sip, especially lying down, is a common cause of pill-induced irritation. Stay upright for a few minutes afterward.

What if I miss a dose — should I double up?

No. Skip the missed serving and resume four capsules the next day. There's no evidence doubling recovers anything, and it doubles the zinc in a single sitting — the ingredient most likely to cause nausea at higher single doses. Nothing about the product's proposed mechanism suggests a missed day needs compensating for.*

Can I take Transfer Factor Max with coffee?

No study has looked at this specific combination, so nobody can answer it precisely. Generally, coffee and tea contain polyphenols that can modestly reduce absorption of some minerals, and zinc is a mineral. Water is what the label specifies. If coffee is part of your breakfast, taking the capsules with an actual glass of water alongside the meal is a fix that costs nothing.

Can I take Transfer Factor Max with my other supplements?

Usually yes, with one note. Max contains zinc at 90% of the Daily Value plus IP-6, which is chemically the same compound as phytic acid and binds minerals. If you also take separate zinc, iron, calcium or magnesium, spacing those a few hours from Max is a low-cost precaution. No human study tests that combination in either direction, so this is sensible caution rather than a proven interaction. Anyone on prescription medication — particularly immunosuppressants — should talk to a healthcare provider before adding an immune-active supplement. We go through the medication classes worth asking about in our guide to side effects, safety and drug interactions.*

Does it matter what kind of food I take it with?

Slightly, and mostly for the vitamin D3. Research from Dawson-Hughes and colleagues found peak absorption of supplemental vitamin D3 averaged about 32% higher with a meal containing a typical amount of fat than with a fat-free meal — so eggs, yogurt, nuts or avocado beat dry toast and black coffee. Keep the size of that in perspective: a separate study found meal conditions changed measured absorption of vitamin D3 without changing the plasma 25-hydroxyvitamin D response, which is what reflects your actual vitamin D status. Any real meal is fine.*

How long does Transfer Factor Max take to work?

This needs an honest split answer. In the laboratory sense, the peer-reviewed 2024 trial measured changes in immune-surveillance biomarkers within one to two hours of a single serving. But a biomarker moving in a blood sample isn't the same as a person feeling different, and no trial has measured how anyone felt at any time point — so there's no established timeline for subjective effects, because subjective effects haven't been studied. Practically: a bottle is 120 capsules, a 30-day supply at four per day, and there's a 30-day money-back guarantee — so one bottle is roughly the natural evaluation window.*

Can I take more than four capsules a day?

We wouldn't recommend exceeding the label serving without talking to a healthcare provider. Four capsules is the manufacturer's specified amount, it already delivers 90% of the Daily Value of zinc, and more is not automatically better with immune-active ingredients — a well-known dose-ranging trial of a maitake extract reported some immune measures stimulated at certain doses and depressed at others. There's also no study of any higher serving of this product, so anyone taking more is running an experiment with no data behind it.*

Can I open the capsules and mix the powder into a drink?

The product is designed and studied as an encapsulated supplement, and the peer-reviewed trial gave it that way. Opening capsules changes how and where the contents dissolve, and nothing has been tested that way for this formula — so we can't tell you it performs the same. If swallowing four capsules is difficult, taking them one at a time with plenty of water across a single meal is the better workaround, and 4Life also sells a chewable transfer factor product for people who can't manage capsules at all.

References

4Life Transfer Factor Max product page and Product Information Sheet, 4life.com. Directions for Use ("Take four (4) capsules with 240 ml (8 oz) water daily. For best results, take with food."), Product Specifications (serving size four vegetable capsules; 30 servings per container), and ingredient list. Accessed August 14, 2026.
Yu, L., Iloba, I., Cruickshank, D., & Jensen, G.S. (2024). Feasibility Trial Exploring Immune-Related Biomarkers Pertaining to Rapid Immune Surveillance and Cytokine Changes after Consuming a Nutraceutical Supplement Containing Colostrum- and Egg-Based Low-Molecular-Weight Peptides. Current Issues in Molecular Biology, 46, 6710–6724. Double-blind, randomized, placebo-controlled crossover pilot; blood draws pre-consumption and at 1, 2 and 24 hours. Methods describe clinic visits scheduled 7:00–11:00 a.m. to minimize circadian effects, an enrollment requirement of consistent bland breakfasts on visit days, abstention from exercise and other supplements that morning, and the encapsulated test product "provided with water and consumed in the presence of clinic staff."
Dawson-Hughes, B., et al. Dietary Fat Increases Vitamin D-3 Absorption. Journal of the Academy of Nutrition and Dietetics. Reported peak (12-hour) absorption of supplemental vitamin D3 averaging ~32% higher when taken with a meal containing a commonly consumed amount of fat than with a fat-free meal.
Meal conditions affect the absorption of supplemental vitamin D3 but not the plasma 25-hydroxyvitamin D response to supplementation. PubMed 23427007. The counterweight study: measured absorption differed by meal condition without a corresponding difference in plasma 25(OH)D response.
Memorial Sloan Kettering Cancer Center, Integrative Medicine — IP-6 (About Herbs database). IP-6 (inositol hexaphosphate) is the same compound as phytic acid/phytate; mineral chelation and interaction with mineral supplements are documented.
Levine, M., et al. (1996). Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance. Proceedings of the National Academy of Sciences, 93(8), 3704–3709. Oral doses up to ~200 mg are essentially completely absorbed; bioavailability declines at higher doses, to roughly one-third for a single 1,250 mg dose. Gastrointestinal absorption and renal tubular reabsorption are both saturable.
Grases, F., Costa-Bauza, A., Perelló, J., Isern, B., Vucenik, I., et al. (2006). Influence of concomitant food intake on the excretion of orally administered myo-inositol hexaphosphate in humans. Journal of Medicinal Food, 9(1), 72–76. n=6; 400 mg dose taken on an empty stomach, on an empty stomach with an alkalinising agent, and on a full stomach; no meaningful difference in absorption between conditions.
Survival and digestibility of orally-administered immunoglobulin preparations containing IgG through the gastrointestinal tract in humans. Nutrition Journal, 2015;14:22. Review reporting that orally administered bovine IgG survives gastric exposure and resists proteolytic digestion, with intact IgG recovered in stool ranging from trace amounts up to ~25% of the amount ingested. Note: this concerns intact immunoglobulins, not the low-molecular-weight peptides in Transfer Factor Max.
Deng, G., et al. (2009). A phase I/II trial of a polysaccharide extract from Grifola frondosa (maitake mushroom) in breast cancer patients. Journal of Cancer Research and Clinical Oncology. Oral dose-ranging trial reporting dose-dependent immunological effects in both directions — cited here only as evidence that "more" is not automatically better with immune-active ingredients.
4Life Satisfaction / Shipping & Returns policy, 4life.com — 30-day money-back guarantee terms. See the guarantee page for specifics.

*These statements have not been evaluated by the Food and Drug Administration. Transfer Factor Max is a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease. This article summarizes the manufacturer's published directions for use, the documented protocol of a published human trial, and general absorption research on named nutrients. It is educational content, not medical advice, and it is not a claim that any timing, meal or dosing pattern produces a health outcome. Individual results may vary. Consult your healthcare provider before starting any supplement — particularly if you are pregnant, breastfeeding, managing an autoimmune condition, or taking prescription medication including immunosuppressants. Follow the directions on your own bottle, which are authoritative over any summary here.